Institutional Tissue Banks Policies & Standard Operating Procedures MIDGAM

Summary

These standard operating procedures have been compiled by the Israeli Biobank Network based on templates taken from the website of the Canadian Tumor Repository Network (CTRNet) with additional content from standard operating procedures generously shared by the M.D. Anderson Cancer Center. As the Israeli Biobank Network is a new entity, some SOP sections are incomplete and will be updated.

The attached document contain a collection of policies and standard operating procedures (SOPs) used by the Israeli Biobank Network. The document also contain forms used by the biobank network and an appendix with other material applicable to biobanking

 

Policies in the document

ITB POLICY 1.0 - INFORMED CONSENT
ITB POLICY 1.1 - MATERIAL AND INFORMATION HANDLING
ITB POLICY 1.2 - PRIVACY AND SECURITY
ITB POLICY 1.3 - ETHICS
ITB POLICY 1.4 - RECORDS AND DOCUMENTATION
ITB POLICY 1.5 - INVESTIGATOR ACCESS TO BIOSPECIMENS AND CLINICAL DATA
ITB POLICY 1.6 – INSTITUTIONAL SCIENTIFIC COMMITTEE
ITB POLICY 1.7 - REFERENCES
 

Standard Operating Procedures  in the document

GENERAL SOPS
GEN 2.1.1.: OBTAINING INFORMED CONSENT
GEN 2.2.1: LABELING AND TRACKING MATERIALS
GEN 2.2.2: INVENTORY VERIFICATION
GEN 2.3.1: BIOHAZARDOUS MATERIAL WASTE MANAGEMENT
GEN 2.4.1: ADMINISTRATION OF SOPS
GEN 2.4.2: JOB DESCRIPTION, ROLES AND RESPONSIBILITIES


BIOSPECIMEN SOPS
MAN 3.1: STERILE SPECIMEN COLLECTION
MAN 3.2: STANDARD BIOSPECIMEN PROCESSING


BLOOD SOPS
MAN 4.1: BLOOD COLLECTION
MAN 4.2: BLOOD PROCESSING & STORAGE
MAN 4.3: BLOOD DERIVATIVES - EXTRACTION OF DNA
MAN 4.4: BLOOD DERIVATIVES - EXTRACTION OF RNA


TISSUE SOPS
MAN 5.1: TISSUE COLLECTION (& TRANSPORTATION TO PATHOLOGY)
MAN 5.2: TISSUE YIELDING
MAN 5.3: SNAP FREEZING OF TISSUE
MAN 5.4: FREEZING OF TISSUE IN OCT
MAN 5.5: TISSUE PRESERVATION BY FFPE
MAN 5.6: SECTIONING PARAFFIN & OCT EMBEDDED TISSUE
MAN 5.7: H & E STAINING OF TISSUE SECTIONS
MAN 5.8: TISSUE DERIVATIVES - EXTRACTION OF DNA
MAN 5.9: TISSUE DERIVATIVES - EXTRACTION OF RNA
MAN 5.10: TMAS FROM PARAFFIN-EMBEDDED BLOCKS
MAN 5.11: SAMPLE RETRIEVAL
MAN 5.12: SAMPLE DESTRUCTION


QUALITY CONTROL (QC) SOPS
QC 6.1: ASSESSING QUALITY OF TISSUE SPECIMENS
QC 6.2: ASSESSING QUALITY/PURITY OF EXTRACTED NUCLEIC ACIDS


RELEASE SOPS
REL 7.1: SAMPLE SHIPPING AND TRANSPORTATION
REL 7.2: COMPLETION OF AN MTA
REL 7.3: MATERIAL REQUEST AND RELEASE


BILLING SOP
FIN 8.1: BILLING


SECURITY SOPS
SEC 9.1: DATA MANAGEMENT
SEC 9.2: INVESTIGATOR ACCESS TO THE ITB

 

Forms in the document

FORM 1 - CONFIDENTIALITY AGREEMENT FOR EMPLOYEES
FORM 2 - SPECIMENS REQUEST FORM OR INVESTIGATOR APPLICATION FORM
FORM 3 - SCIENTIFIC COMMITTEE PROTOCOL
FORM 5 – MIDGAM – EXPLANATORY LEAFLET – ENGLISH TRANSLATION
FORM 6 - TISSUE COLLECTION & PROCESSING WORKSHEET
FORM 7 - BLOOD COLLECTION & PROCESSING WORKSHEET
FORMS 8.1-8.4 - ASSESSING QUALITY OF TISSUE SPECIMENS - EXAMPLES
 

Appendices in the document

APPENDIX A - FLOW CHART OF WORK (EXAMPLE – SHEBA MEDICAL CENTER ITB – CERTAIN PROCEDURES MAY VARY ACCORDING TO ITB)

  1. GENERAL
  2. O.R. PROCESSING AND ALIQUOTING
  3. PATHOLOGY/DESIGNATED LAB: PROCESSING AND ALIQUOTING

APPENDIX B - BUFFERS & REAGENTS PREPARATIONS FOR DNA EXTRACTION
APPENDIX C - SIMPLE LETTER OF AGREEMENT (EXAMPLE – REQUIRES TRANSLATION INTO HEBREW)
APPENDIX D - ITB FEE SCHEDULE (REQUIRES CONSENSUS – NOT FINALIZED)
APPENDIX E - MASTER SOP & POLICY TRAINING RECORD
APPENDIX F – LN2 TANK LEVEL LOG FOR SMALL TANKS
 

Attachments

Citation

Cohen, Yehudit. User menu My account Log out Institutional Tissue Banks Policies & Standard Operating Procedures MIDGAM. The Molecular Methods Database. 2013/12/20

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